Presurgical brain mapping of language processing with fMRI: state of the art and tendencies

Presurgical brain mapping of language-eloquent cortex aims to minimize its injury during neurosurgery in patients with tumors and drug-resistant epilepsy, thereby, preserve their quality life. Two main goals language are identify the localization lateralization regions involved language. Gold standards for them intraoperative Wada test, respectively; however, due some limitations these techniques, non-invasive preliminary becomes reasonable. During last years, fMRI has been widely applied such purposes. Our literature review focuses on innovations actual tendencies which spread field via decade. State-of-the-art knowledge organization language, underpins processing fMRI, is briefly described article. Contemporary studies validity considered. Strategies presurgical mapping, as application tractography addition combined analysis tasks well resting-state also discussed. Well-established production comprehension, new experimental developments this field, listed described.